Instruction
For each of the following questions, refer to the graph first, and then provide an explanation:
1. Jamie was at her dorm room when her roommate Stephanie, was sent to the ER after learning that she was suspected of having Haemophilus infleunzae Meningitis. Jamie was concerned that she would become ill as well, even though she had received the HIB vaccine. Which part of the graph represents Jamie's immune response to being exposed to the H. influenzae? Explain
2. Which part of the graph represents Stephanie's immune response to being exposed to H. influenzae? Explain
3. A few days earlier, Jamie had stepped on a nail which penetrated her flip-flops near the campus center. She had not received a booster shot for tetanus in over 15 years. Which part of the graph represents Jamie's potential transmission of the tetanus endospore, while her immune system is simultaneously defending against H. influenzae? Explain
John is a 28 year-old man that works in a large city. One week ago, he started having a fever with peaks to 40°C each evening, and also complaining of malaise, night sweats, muscle aches, over a period of 4 days. Two weeks earlier, he had helped out on his uncle's cattle farm as part of his vacation. John recalled that two years ago, he also became ill about two weeks after tending to cattle and sheep at his uncle's farm. At that time, he was diagnosed with brucellosis caused by B. abortus.
4. It appears that this year John had been exposed to both B. abortus and B melitensis. Use the graph to identify the initial immune response to each pathogen. Explain. What type of immunity did John have for B abortus from the following choices (natural, artificial, passive, active)
5. Use the graph to identify peak antibody production against each pathogen. Explain
6. Which part of the graph would represent John's immune response to B. suis if he were to be infected with that pathogen next time he goes to the farm? Explain
These bacteria are transmitted via zoonoses. Identify the differences in transmission for each pathogen. In general, what is the degree of mortality of the illness to humans?